Journal: Frontiers in Neurology

Article Title: “Rogue” [DEspR+CD11b+] neutrophil subset correlates with severity in spontaneous intracerebral hemorrhage

doi: 10.3389/fneur.2022.935579

Figure Lengend Snippet: Spearman rank correlation coefficients ( r) among clinical and radiological measures of sICH severity ( n = 13).

Article Snippet: For this pilot observational study, correlations were calculated using the Spearman Rank Order correlation test (GraphPad PRISM version 9.3), and power calculations were determined using the SigmaPlot 11.0 software.

Techniques:

Journal: Frontiers in Neurology

Article Title: “Rogue” [DEspR+CD11b+] neutrophil subset correlates with severity in spontaneous intracerebral hemorrhage

doi: 10.3389/fneur.2022.935579

Figure Lengend Snippet: Spearman rank correlation analyses of three neutrophil-based markers with sICH severity: GCS-score, IPH-volume, and PHE-volume. Correlation of GCS-score [t-1] with (A) DEspR+CD11b+ neutrophil counts, K/μl (“rogue” Ns [t-1]). (B) NET-forming neutrophil counts, K/μl, (NET+Ns [t-1] and (C) neutrophil lymphocyte ratio (NLR). Correlation of IPH volume [t-1] with: (D) DEspR+CD11b+ neutrophil counts, K/μl (“rogue” Ns [t-1]), (E) NET-forming neutrophil counts, K/μl (NET+Ns [t-1], and (F) neutrophil-lymphocyte ratio (NLR). Correlation of PHE-volume [t-1] with (G) DEspR+CD11b+ neutrophil counts, K/μl (“rogue” Ns [t-1]), (H) NET-forming neutrophil counts, K/μl (NET+Ns [t-1]), and (I) neutrophil-lymphocyte ratio (NLR). All measurements were obtained on the same day ± 1-day [t-1] as the day of flow cytometry analysis; red • symbols represent sICH-subject nonsurvivors; gray • symbols mark values for sICH-subject survivors; r , Spearman rank correlation coefficient; p B , p -value with Bonferroni correction. ns, not significant.

Article Snippet: For this pilot observational study, correlations were calculated using the Spearman Rank Order correlation test (GraphPad PRISM version 9.3), and power calculations were determined using the SigmaPlot 11.0 software.

Techniques: Flow Cytometry

Journal: Frontiers in Neurology

Article Title: “Rogue” [DEspR+CD11b+] neutrophil subset correlates with severity in spontaneous intracerebral hemorrhage

doi: 10.3389/fneur.2022.935579

Figure Lengend Snippet: Spearman rank correlation analysis of three neutrophil-based markers and sICH outcomes: admission ICH score and 90-day mRS. Correlation of admission ICH score with: (A) DEspR+CD11b+ neutrophil counts, K/μl, (“rogue” Ns [t-1]), (B) NET-forming neutrophil counts, K/μl, (NET+Ns [t-1], and (C) neutrophil-lymphocyte ratio (NLR). Correlation of 90-day mRS with: (D) DEspR+CD11b+ neutrophil counts (“rogue” Ns [t-1]), (E) NET-forming Ns (NET+Ns [t-1], (F) neutrophil lymphocyte ratio (NLR). [t-1], on day of flow cytometry; Red • symbols represent sICH-subject non-survivors; gray • symbols mark values for sICH-subject survivors; r , Spearman rank correlation coefficient; and p B , p -value with Bonferroni correction.

Article Snippet: For this pilot observational study, correlations were calculated using the Spearman Rank Order correlation test (GraphPad PRISM version 9.3), and power calculations were determined using the SigmaPlot 11.0 software.

Techniques: Flow Cytometry

Journal: Frontiers in Neurology

Article Title: “Rogue” [DEspR+CD11b+] neutrophil subset correlates with severity in spontaneous intracerebral hemorrhage

doi: 10.3389/fneur.2022.935579

Figure Lengend Snippet: Spearman rank correlation analysis of top 3 peripheral neutrophil markers with clinical and radiological measures of sICH severity ( n = 13).

Article Snippet: For this pilot observational study, correlations were calculated using the Spearman Rank Order correlation test (GraphPad PRISM version 9.3), and power calculations were determined using the SigmaPlot 11.0 software.

Techniques: Marker

Journal: Frontiers in Neurology

Article Title: “Rogue” [DEspR+CD11b+] neutrophil subset correlates with severity in spontaneous intracerebral hemorrhage

doi: 10.3389/fneur.2022.935579

Figure Lengend Snippet: Spearman rank correlation analysis of three neutrophil-based markers among each other. (A) Correlation of same day (t-1) DEspR+CD11b+ neutrophil counts, (Rogue Ns, K/μl), (t-1: # Rogue Ns) with neutrophil-lymphocyte ratio (NLR); (B) correlation of t-1:# Rogue Ns with NET-forming neutrophil counts (NET+Ns, K/μl), (t1: # NET+Ns); and (C) correlation of t-1: # NET+Ns with NLR. Ns, neutrophils; t1: day of flow cytometry; red • symbols represent sICH nonsurvivors; gray • symbols mark values for sICH survivors; r , Spearman rank correlation coefficient; p B , p -value with Bonferroni correction. n.s. not significant.

Article Snippet: For this pilot observational study, correlations were calculated using the Spearman Rank Order correlation test (GraphPad PRISM version 9.3), and power calculations were determined using the SigmaPlot 11.0 software.

Techniques: Flow Cytometry

Journal: Frontiers in Neurology

Article Title: “Rogue” [DEspR+CD11b+] neutrophil subset correlates with severity in spontaneous intracerebral hemorrhage

doi: 10.3389/fneur.2022.935579

Figure Lengend Snippet: Spearman rank correlation: combinatorial analysis sICH cohort ( n = 13).

Article Snippet: For this pilot observational study, correlations were calculated using the Spearman Rank Order correlation test (GraphPad PRISM version 9.3), and power calculations were determined using the SigmaPlot 11.0 software.

Techniques: